Rheumatoid Arthritis: Symptoms to Know

Rheumatoid arthritis (also known as RA) can be a very painful condition. For many patients, RA pain is severe enough to impact their everyday lives. Below, we will go over the most common RA symptoms. Diagnosing and treating RA early is the best way to slow this disease’s progress. Therefore, it’s important to know which symptoms to look for.

What is Rheumatoid Arthritis?

Rheumatoid Arthritis is an autoimmune disease that causes painful swelling and inflammation. Autoimmune diseases are caused by a person’s immune system attacking healthy parts of the body instead of unhealthy infections. This can cause chronic pain, swelling, and other symptoms. For RA patients, this pain is usually in and around a person’s joints. However, RA can also affect other parts of the body.

Key Symptoms and Warning Signs

The main RA warning sign is pain or stiffness in a person’s joints. Other symptoms include changes to a joint’s appearance, problems walking, mobility issues, and general feelings of malaise. Because many RA symptoms are very general, it can be tough to diagnose this disease. If you have these symptoms, it is important to bring your concerns to a doctor.

Current RA Treatments

While there is no cure for RA, there are treatment options. Most RA patients will take medication to manage their disease. These medications can help to reduce pain and also limit inflammation. Some RA patients might also need occupational therapy or surgery.

How a Clinical Trial Can Help Your Symptoms

If you are struggling with RA, then traditional treatments might not be enough. Some patients try numerous medications and still deal with painful symptoms. Clinical trials might be the answer for these patients. Clinical trials allow you to try the latest treatments with doctor supervision. All medications, lab work, exams, and doctor’s appointments are covered free of charge. Patients might also be compensated.

If you are an RA patient over the age of 18, you might qualify for a trial at DM Clinical Research. To learn more about our RA study, call the study’s direct line at 281-401-9803.

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Rheumatoid Arthritis Day Brings in Help for Chronic Sufferers

Suffering from a condition like rheumatoid arthritis (RA) can not only be physically painful, it can also cause serious emotional distress. Patients living with chronic and often misunderstood conditions like RA are tasked with managing their health while educating people around them about their condition. This is something the Rheumatoid Patient Foundation has been working to counteract since 2013 with an annual Rheumatoid Awareness Day.

To recognize the importance of awareness, funding and clinical research for patients with RA, the at-home testing group imaware™ is matching all donations to the Rheumatoid Patient Foundation up to $10,000 through February 12, a full ten days after RA Day 2019.

Finding Relief From Rheumatoid Arthritis

Challenging to treat and still not completely understood, rheumatoid arthritis can make even the smallest tasks an enormous challenge by causing pain, swelling and inflammation of the joints. While treatment options can be limited, many patients do find relief while helping to support others with the condition through clinical trials. Through these trials, patients are able to access cutting-edge treatment and, ideally, slow the progression of RA.

If you or someone you love is battling rheumatoid arthritis, there may be treatment options yet to be explored that can potentially have a lasting impact on the condition. Blazing a trail for future patients while seeking the very latest in treatment designed to improve mobility, alleviate pain and reduce joint damage means you’re able to help yourself while potentially helping others. RA Day has come and gone for 2019, but it’s not too late to make the pursuit of emerging treatment a goal for this year.

Contact us today at DM Clinical to see if you qualify for groundbreaking rheumatoid arthritis clinical trials.

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The Effects of Psoriatic Arthritis on the Body

Effects of Psoriatic Arthritis

Effects of Psoriatic Arthritis, rheumatoid arthritis clinical trials, medical trials, DM Clinical Research has been helping to bring new treatments to the medical field for over ten years. We are the link connecting pharmaceutical and research organizations to caring individuals such as yourself who want to play a part in the advancement of medicine. Effects of Psoriatic Arthritis We have a large network of qualified physicians with a diverse range of specialties. We have conducted hundreds of studies in a wide variety of therapeutic areas that many patients saw improvement in their symptoms. a necessity in developing medicine, they are also an opportunity for patients to receive cutting edge treatment that may not currently be available to the general public. Effects of Psoriatic Arthritis Watch this video to see how you can play an important part in clinical research.

Combining the skin symptoms of psoriasis and the joint pain of arthritis, psoriatic arthritis (PsA) can be difficult to manage. National Psoriasis Foundation research indicates up to 30 percent of people with psoriasis will eventually develop PsA, a chronic condition affecting much of the body.

What Is Psoriatic Arthritis?

A form of arthritis, psoriatic arthritis is most common in middle-age adults but can strike anyone. Treatment for PsA typically targets symptoms and joint damage prevention, because there is no cure for the condition.

Skin, hair and nails are the areas where symptoms are often most noticeable to the naked eye. Psoriasis causes tender, sometimes itchy, patches which can be rough and red to scaly and silvery in color. Most of the time, these patches will form around the feet, hands, elbows and knees but can also affect the scalp. Nails of the fingers and toes can become discolored, thick and pitted, or can exhibit abnormal growth, which extends to them separating fully from the nail bed in places.

Research shows vision problems can also be a symptom of psoriatic arthritis. These symptoms include conjunctivitis, lesions and uveitis. The musculoskeletal system is also affected, including weakening of ligaments, tendons and muscles due to chronic inflammation. Because PsA is an autoimmune condition, the body can also attack already-inflamed joints, tendons and ligaments. Stiffness, swelling and pain are common symptoms of psoriatic arthritis, though patients with PsA sometimes experience periods of remission accompanied by sporadic flare-ups.

Hope for Patients With PsA

If you suffer from psoriatic arthritis, you know it can be a debilitating and disheartening condition. The stress and pain of PsA can also have an impact on your emotional health, causing depression and anxiety in many patients.

At DM Clinical Research, we’re working to be part of the solution, with clinical trials aimed at treating and curing psoriatic arthritis. New medications can help to manage the symptoms of psoriatic arthritis. Contact us today to find out if you qualify for participation in clinical trials.

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What You Need to Know About Clostridium Difficile

Clostridium Difficile Treatment

Clostridium Difficile Treatment, rheumatoid arthritis clinical trials, medical trials, DM Clinical Research has been helping to bring new treatments to the medical field for over ten years. We are the link connecting pharmaceutical and research organizations to caring individuals such as yourself who want to play a part in the advancement of medicine. We have a large network of qualified physicians with a diverse range of specialties. We have conducted hundreds of studies in a wide variety of therapeutic areas that many patients saw improvement in their symptoms. a necessity in developing medicine, they are also an opportunity for patients to receive cutting edge treatment that may not currently be available to the general public. Watch this video to see how you can play an important part in clinical research.

More commonly referred to as C. diff, Clostridium difficile is a bacterium found in the intestines or colons of certain people. The C. diff bacteria is kept in check by the helpful bacteria in your body – until you need to take an antibiotic, reducing the number of those beneficial bacteria. This can result in the condition known as Clostridium difficile colitis.

Symptoms of Clostridium Difficile

Clostridium difficile creates toxins in the body, when it gets out of control. This can cause ulcers, or sores, to form in the intestine. Diarrhea and cramping are usually the first symptoms, followed by feeling like you have the flu. There is also a chance of passing bloody stools in the later stage of a Clostridium difficile infection. Around 14,000 people die from advanced Clostridium difficile each year, so it is important to seek treatment.

Diagnosing Clostridium Difficile

If you are experiencing symptoms that match those of Clostridium difficile, you will need to visit your doctor. If Clostridium difficile is suspected, your doctor will likely ask for a stool sample for testing. Referral to a gastroenterologist is the next step in diagnosing and treating the condition. A further test, called a colonoscopy, is used to assess any damage to the intestines and to look for Clostridium difficile and polyps.

Treatment of Clostridium Difficile

Although antibiotics are the cause of the Clostridium difficile bacteria taking over in the intestine and colon, two other powerful antibiotics are used to treat the condition. There is a treatment that may sound radical, from the patient point of view. It is known as fecal bacteriotherapy, and it involves transplanting another person’s healthy stool inside the patient. This treatment has been shown to be highly effective for curing patients of Clostridium difficile.

DM Clinical Research is committed to helping improve the efficacy of medications to treat conditions such as Clostridium difficile through continuous trial research.

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Rheumatoid Arthritis and Pannus

Rheumatoid Arthritis Treatments

Rheumatoid Arthritis Treatments, rheumatoid arthritis clinical trials, medical trials, DM Clinical Research has been helping to bring new treatments to the medical field for over ten years. We are the link connecting pharmaceutical and research organizations to caring individuals such as yourself who want to play a part in the advancement of medicine. We have a large network of qualified physicians with a diverse range of specialties.

Those who have rheumatoid arthritis, whether you’ve just been diagnosed or have been dealing with the symptoms for some time, need to be aware of conditions that can develop in the later stages of the disease. Pannus is one of those conditions, but what is the link between rheumatoid arthritis and pannus?

What is Rheumatoid Arthritis?

Rheumatoid arthritis is one of the most common autoimmune disease today. This condition, also known as RA, causes the immune system that normally protects your body from illness and other issues to attack the joints, instead. It is considered a systemic disease, which means it can and usually does affect the entire body.

What is Pannus?

Pannus is the thickening of the tissues in the joint caused by the cytokines that are released due to rheumatoid arthritis. As the pannus continues to grow, it fills more and more of the joint, which causes significant pain and can cause permanent damage. Damage to the bones is possible as well, but the most detrimental damage is to the cartilage and the synovium.

The Link Between Rheumatoid Arthritis and Pannus

It is the cytokines, released in the body when you have rheumatoid arthritis, that lead to swelling of the synovium. That swelling then leads to the development of pannus tissues. While pannus usually affects the joints, it can also affect other areas of the body, because of the systemic nature of the disease. This means rheumatoid arthritis and pannus can potentially have an effect on your eyes, your abdomen, and other areas.


With rheumatoid arthritis, the immune system is overactive. Treatments usually include typical OTC pain meds, such as Tylenol for pain management, but also medications specifically formulated for the treatment of RA. These are known as DMARDs, or disease-modifying anti-rheumatic drugs. They work to suppress the overactive immune system. Biological therapies, such as rituximab, can also help by decreasing the number of antibodies the white blood cells produce.


By treating rheumatoid arthritis, you may be able to prevent pannus from developing, or you may be able to slow it down, if it has already started. Effectively treating it can also help prevent other complications, such as osteoporosis, infections, anemia and others. Pannus can develop and progress even with treatment. Still, today’s treatments are more effective than ever at managing symptoms. Managing the disease and related conditions can prevent permanent damage and mobility problems.

DM Clinical Research is helping trial new medications and treatments for rheumatoid arthritis and pannus. This will help create lasting change in the way RA is treated and how pannus is prevented or controlled. Contact us to see if you qualify for any clinical trials and if you would like to help us help others just like you.

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Treatment Options for Psoriatic Arthritis

If you have been diagnosed with psoriatic arthritis, you are likely wondering about treatment options. You will receive a lot of anecdotal accounts of wonder cures as well as treatments that just don’t work. However, it is always best to get your medical advice from the professionals.

There are a number of drugs that patients find effective for treating the symptoms of psoriatic arthritis. Over-the-counter (OTC) medicines, such as ibuprofen, may ease your pain and swelling. If these types of medications do not have any noticeable impact, you may need stronger medications prescribed by a doctor.

OTC Psoriatic Arthritis Drugs

NSAIDs (nonsteroidal anti-inflammatory drugs) are a type of OTC medicine which your doctor may recommend in the first instance. These drugs are designed to treat symptoms such as pain and inflammation for conditions including psoriatic arthritis. Two of the most common examples of OTC drugs which fall under the category of NSAIDs are Ibuprofen which includes the brand names Motrin and Advil, and Naproxen which includes the names Anaprox and Aleve. Your doctor may also prescribe NSAIDs that are not available OTC.

Disease-Modifying Anti-Rheumatic Drugs (DMARDs)

A doctor will discuss DMARDs with you if you need a more effective treatment option for psoriatic arthritis to stem the damage caused to joints. These drugs take longer to start having an impact, and there is also a greater risk of suffering from side effects when taking DMARDs. Sulfasalazine, Leflunomide, Methotrexate and Cyclosporine are examples of DMARDs, which your doctor may recommend combining for more effective relief.

Immunosuppressant Drugs

Immunosuppressants, as the name suggests, are used to suppress symptoms in people who suffer from psoriatic arthritis. This type of drug is associated with the potential for serious side effects and is usually reserved for patients with severe symptoms and who are under close scrutiny from a doctor.

TNF-Alpha Inhibitors

The purpose of taking TNF-alpha inhibitors is twofold: The drug can help with the symptoms of both psoriasis and psoriatic arthritis. Much like with immunosuppressants, TNF-alpha inhibitors can result in the patient experiencing serious side effects.

At-Home & Lifestyle

Heat and cold treatments are often recommended by doctors to ease the symptoms of psoriatic arthritis. Speak to your doctor about how to apply heat and cold for the specific symptoms you are experiencing.

It is also important not to overdo it at home when it comes to everyday activities, such as sitting, walking, lifting, etc. Your doctor may refer you to physiotherapist to help you make lifestyle adjustments. Diet also plays an important part in managing psoriatic arthritis symptoms, so if your weight is putting strain on your joints, it is time to make some changes.

DM Clinical Research is dedicated to finding cures for conditions such as psoriatic arthritis through clinical research. Call today and ask about study participation.

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Are bDMARDs the Only Hope for Psoriatic Arthritis?

Around 30% of people who suffer from the skin disease psoriasis also live with an ailment called psoriatic arthritis. While problems with the skin manifest with this autoimmune disease, for people with psoriatic arthritis, it also affects the joints. Itchy, scaly skin along with crumbling nails are what most people think of when they hear the term psoriasis, but the inflammatory arthritis that affects the joints can be a source of great discomfort.

Autoimmune diseases are those which cause the body to essentially fight against itself. The body’s immune system attacks healthy tissue. The skin is involved in psoriasis. Both the skin and joints come underattack in psoriatic arthritis, which causes inflammation. The joints swell and produce pain. The condition must be treated aggressively, and needs to be caught in the early stages in order to reduce the likelihood of permanent damage to joints and tissue.

Treatment of Psoriatic Arthritis

Biologic disease-modifying anti-rheumatic drugs, or bDMARDs, are used in the treatment of psoriaticarthritis. These drugs are used to slow the progression of rheumatoid arthritis. There are different types of bDMARDs used in the treatment of psoriatic arthritis. The specific drug used to treat a patient is identified depending on the severity of the condition and symptoms, how the patient responds to treatments and other significant factors.

How bDMARDs Help Psoriatic Arthritis

Biologic DMARDs are made from living cells and have a tendency to be highly expensive. These types of drugs specifically target immune proteins called cytokines. They are very potent. Even though psoriaticarthritis cannot be cured, it can be controlled and perhaps put into remission with the use of bDMARDs. Existing joint damage is taken into account when prescribing a bDMARD or a combination of drugs.

When a bDMARD Fails

Treatment for psoriatic arthritis is not purely straightforward. If a specific bDMARD does not work or is not working efficiently, the doctor will need to make an adjustment and choose another drug or combination of drugs.

Alternative Treatments for Psoriatic Arthritis

If you have been diagnosed with psoriatic arthritis, your doctor will most likely begin treatment with NSAIDS, depending on the severity of your condition at the time of diagnosis. Disease-modifying anti-rheumatic drugs (DMARDs) are used to treat symptoms that have progressed in severity. There are also new oral treatments available. These treatments target inflammation by inhibiting specific molecules that cause it.

Once you are diagnosed, your doctor will work with you to find the most effective treatment. It is important to slow the progression of psoriatic arthritis as early as possible to prevent joint damage.

At DM Clinical Research, we are always discovering new ways to treat diseases. We invite you to contact us to find out more about our clinical trials.

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Is Rheumatoid Arthritis the Same as Osteoarthritis and are Medical Trials Available?

People are sometimes confused when it comes to an understanding of the difference between osteoarthritis (OA) and rheumatoid arthritis (RA). Both diseases cause pain and swelling in the joints, especially in the extremities such as the hands, knees, and hip. And, both conditions can affect movement and mobility as well as have a negative impact on day to day activities. Even though many of the noticeable symptoms are similar, the underlying causes, as well as the types of treatment, are very different. Currently, medical trials are underway at DM Clinical Research in Tomball seeking new therapies for RA. If you suffer from joint pain, it is important to understand the difference between the two types of arthritis which can help you better manage the disease. If you have been diagnosed with RA, you may be a candidate for DM’s RA medical trial which is currently underway.

Osteoarthritis (OA) arises from the deterioration of the soft tissue in the joints. Under normal conditions, this tissue acts as a cushion between the bones that connect at the joint. When the tissue wears away or deteriorates, the two bones come in contact causing pain, stiffness, and swelling. This problem often occurs in the hip or knee due to the wear and tear of walking or running. Injuries to the joints may cause inflammation and also bring on osteoarthritis. Most often osteoarthritis is treated surgically by replacing or repairing the affected joint.

Although rheumatoid arthritis (RA) exhibits similar symptoms, the causes of the disease are very different. RA is caused when the body’s auto-immune system malfunctions and mistakenly attacks the body. This attack is usually focused in the joints and results in swelling, pain, inflammation, and reduced mobility. A number of treatment options are available, but early identification of RA is important to mitigate the effects of the condition. Medical research is continuing in order to understand RA and its underlying causes. DM Clinical Research of Tomball is currently conducting medical trials to study the benefits of new treatments for RA.

If you are eighteen years of age or over, been diagnosed with RA, and currently take medications for RA, you may qualify to participate in our RA medical trial. DM Clinical is conducting medical trials to assess the benefits of new treatments for RA that could reduce or prevent joint damage, relieve pain, and improve mobility. Because these treatments are so new, they are not yet available to the general public. As a result, medical trial participants have access to the very latest in pharmaceutical medications that may offer improved outcomes.

If you feel you may be a candidate for our RA medical trial, please give us a call at our RA hotline, 281-401-9803. If you are selected as a participant, you will receive all treatment medications free, as well as all doctor visits and lab work. In some cases compensation is offered for time and travel. DM Clinical Research is located in Tomball, Texas and is a leader in clinical research trials studying new treatments in RA, Alzheimer, Type 2 Diabetes, and other conditions. Because DM Clinical is researching new approaches and medications for various diseases, participants in one of our medical trials offer benefit not currently available from the medical community. To see if you qualify, please contact us at our primary office number, 281-517-0550.

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