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Quick Facts About Ulcerative Colitis

Ulcerative colitis is the inflammation of the colon (the large intestine). A long-term condition, ulcerative colitis is quite chronic, and in extreme cases, it leads to ulcers (and bleeding) in the lining of the large intestine. Learn more about ulcerative colitis below:

  • Up to 700,000 people in the United States suffer from ulcerative colitis, and there is no known cure for the condition.
  • Early warning signs are diarrhea (with streaks of blood and mucus), abdominal pain, anemia, weight loss, and so on. Symptoms are more pronounced in the morning and may cease for months even without treatment. However, they always return.
  • The causes of ulcerative colitis remain unclear, but contributing factors include genetics (20% of patients have a family history of the disease or of Crohn’s disease) and lifestyle choices (diet, poor hygiene, cigarette smoking, etc.).
  • The disease may also be caused by an autoimmune reaction to a nonexistent infection or a continued response to an infection that has already been eliminated.
  • While ulcerative colitis can affect people of any age, teenagers and young adults between 15 and 30 years old are at a higher risk.
  • As mentioned above, ulcerative colitis cannot be treated completely. However, it can be managed with medications and lifestyle changes.

There are a couple of clinical trials looking to develop a permanent cure for ulcerative colitis. If you’re suffering from the condition, participating in a trial allows you to enjoy top-quality care. You also gain free access to new medications that are not yet available to the general public.

To enroll, please visit DM Clinical. For any inquiries, please call 281-517-0550.

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How to Know If You Have Hypercholesterolemia

A high blood cholesterol level is commonly caused by ingesting food items with high-fat content. However, pure/familial hypercholesterolemia is a genetic abnormality that causes people to have high levels of cholesterol irrespective of their dietary or lifestyle choices. Only about 0.3% of the American population struggle with this condition but a majority of them (about 90%) remain undiagnosed and have no idea that their condition was caused by a genetic disorder.

Causes

Hypercholesterolemia affects the liver’s ability to produce and recycle cholesterol, leading to a buildup in the body. The condition occurs in 2 forms: homozygous familial hypercholesterolemia (HoFH) and heterozygous familial hypercholesterolemia (HeFH). HoFH occurs when the condition is inherited from both parents, and HeFH when inherited from one parent. HoFH presents more severe symptoms than the latter.

Common symptoms

People suffering from pure hypercholesterolemia are born with the condition but the symptoms are never apparent until after many years. Here are some common symptoms associated with hypercholesterolemia:

  • A Small, yellowish buildup of cholesterol under the patient’s eyes or close to their eyelids.
  • Wax-like deposits of cholesterol under the skin.
  • Tiny bumps around the eyes, elbows, hands, and knees.
  • Chest pain.

Complications from hypercholesterolemia

If untreated, hypercholesterolemia increases the risk of a heart attack. Men that have the condition will likely suffer from a heart attack between the ages of 40 and 50, and 85% of them will have suffered from a heart attack before they are 60 years old. Women suffering from hypercholesterolemia are liable to have a heart attack between ages 50 and 60.

People that suffer from the extremely rare HoFH are at risk of a heart attack and death before the age of 30.

If you have been diagnosed with hypercholesterolemia, please reach out to DM Clinical Research. We are working on effective treatments for hypercholesterolemia and you stand a chance of being enrolled in a clinical trial.

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C. Diff Found to Last Longer and Affect Even the Non-elderly

  1. Diff stands for Clostridium Difficile. It’s a bacterial infection of the colon that can cause life-threatening conditions if not treated. The Center for Disease Control (CDC) estimates about 14,000 people die each year from this infection. It’s typically treated with antibiotics, but since antibiotics destroy both bad and beneficial bacteria, it opens the door for a re-infection because the “good” bacteria isn’t present to fight it.

Previously though to affect mostly the elderly (defined as 65 or older), recent studies have found C. diff has a high chance of reoccurrence for the non-elderly, too. The CDC reports that 1 in 5 who have had C. diff will get it again, regardless of age. A study conducted in December of 2017 by PlosOne estimated that those who previously had a C. diff infection were eight times more likely to experience gastrointestinal issues than those who never had C. diff. There is still so much to learn about how and why it occurs in order to facilitate new treatments.

Symptoms

  • Diarrhea 10-15 times daily
  • Abdominal cramping
  • Rapid heart rate
  • Fever
  • Nausea
  • Bloody stool

Joining the Fight

Studies on C. diff are still being performed to better understand the infection and re-infection of patients and how to best treat or eliminate the issue.  At DM Clinical Research we are dedicated to finding out more through our clinical studies. Call us today to find out how you can help us learn more about C. diff and how it affects the elderly and non-elderly alike.

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Ulcerative Colitis Medical Research Trials Are Currently Underway

Ulcerative colitis can be a debilitating illness causing moderate to severe abdominal symptoms including:

  • Abdominal pain and discomfort
  • Weight loss and fatigue
  • Blood in stool
  • Frequent diarrhea, and
  • Reduced appetite

These symptoms are not only uncomfortable and painful but are also very disruptive to everyday activities such as work, eating, time with family, etc. This condition is caused by inflammation of the lining of the colon which in turn is caused by a number of factors including infections, inflammatory bowel disease, allergic reactions, or microscopic colitis.

While medical research is looking for answers, there is no known cure for ulcerative colitis, and today’s treatment regimens focus on controlling symptoms, reducing pain, and lessening patient discomfort. Current medications focus on reducing inflammation and allowing the colon lining to heal naturally. Also, medications can be used to reduce incidents of diarrhea, pain, and bleeding. These treatments may also reduce the frequency of inflammatory flare-ups.

Because there is no known cure for ulcerative colitis, medical research today is focused on new medications and treatments to improve the ability of doctors to treat patients with this condition. DM Clinical Research is a leading provider of clinical trials researching new medical therapies for a variety of diseases and conditions. Currently DM Clinical is conducting medical research trials evaluating the benefits of new medications for treating ulcerative colitis. To assist with this research, DM is looking for qualified participants to join us in this exciting effort. You may be eligible to participate if you are between the ages of 18 and 80. If you are selected, you will receive the latest medications and treatments under review, all doctor consultations, lab work and study materials free of charge. Also, you may qualify for compensation for time and travel. The patients of our clinical center often come with a question about a perfect drug for potency. We always say that it can be determined only after they try several different pills. You know, based on their feedback, the drug on which they stop their choice most often is Cialis. Men love the durability and efficiency of this drug.

To find out if you are a candidate for this study, or any of our studies currently underway, call our offices at 281-517-0550. When you call you can speak with one of our professional staff who will explain our processes, discuss all qualifications for any of our current medical research, and answer all your questions. If you suffer from ulcerative colitis or believe you may be a candidate for our study you can obtain the newest medications available anywhere, free of charge, and realize health benefits not currently available anywhere else.

You owe it to yourself to join our study if you qualify. Your participation in our medical research may not only help your personal condition but additional research information which helps other UC sufferers. Give our offices a call or connect with us using the contact form on this website. You’ll be glad you chose to join us, 281-517-0550.

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